Intrapulmonary penetration of voriconazole in patients receiving an oral prophylactic regimen.
نویسندگان
چکیده
Voriconazole penetrated well into the pulmonary epithelial lining fluid (ELF) in lung transplant patients receiving oral prophylaxis. The ELF concentrations exceeded those of the plasma, with an average ELF-to-plasma ratio of 11 (+/-8). A strong association between plasma and ELF concentrations (r(2) = 0.95) was noted.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 50 5 شماره
صفحات -
تاریخ انتشار 2006